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What really happens in my body when I get herpes before menstruation?
8 أكتوبر 2014
رأي ثانوي

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د. Zakia Dimassi طب الأطفال
Herpes labialis (cold sore, fever blister) is a highly prevalent condition; approximately one-third of all infected patients get relapses of the infection. Herpes labialis is characterized by a rash of the skin and mucous membranes (in particular, the lips) described as erythema (redness) and blisters that are associated with a burning sensation and pain. It is a benign condition that typically is self-limited and heals within 10 days. Herpes labialis is contagious for individuals who have not been previously infected by the virus and for those with weakened immune systems (e.g., those with HIV infection or undergoing chemotherapy, or infants). In addition, herpes labialis infection can result in genital herpes through orogenital contact.
Herpes labialis is caused by herpes simplex virus type 1 (HSV-1). Infection with type 2 virus can also lead to (primary) herpes labialis, but this type rarely causes a relapse of the infection. The primary infection with HSV-1 usually occurs before the age of 20 years. Antibodies against the virus can be found in about 80% of all adolescents.
After primary infection, the virus hides and assumes a dormant state in the ganglion, where it lies latent throughout the individual’s lifetime. Stimuli such as fever, menstruation, sunlight, and upper respiratory infections can reactivate the virus, after which it returns to the skin epithelial cells through the nerve. In contrast to the primary infection, during which all oral mucosa can be affected, relapsing infections are limited to the mucosa of the hard palate or, in older children and adults, the lips. The number of relapses decreases after the age of 35 years.
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