Things that you need to remark:

1- When do they occur (with strenuous exercise? at rest? if you're fatigued?)

2- How often do you get those twitches? And how long do they last?

3- Are you on any medications that may alter your calcium levels in the blood (athletes resort to diuretics to dry up their bodies - diuretics cause hypocalcemia, or low calcium in the blood, which in turn leads to muscle cramps)

4- Sports: are you overworking your muscles?

Here’s what I recommend you should do:

For reassurance, take a serum electrolytes (BUN, creatinine,
calcium, magnesium) levels; if you have deficiency, then you will need
supplementation – talk with your doctor for this matter.

A few tips that could also help include:

• Passive
  stretching and massage of the affected muscle: this will help ease the
  pain of an acute attack. So what you need to do is to straighten the
  affected leg while bending the ankle upward (dorsiflexion), or heel walk
  until the acute pain fades.


• Regular
  stretching of the calf muscles throughout the day: may help to prevent
  acute attacks. You could do stretching three times daily or before going
  to bed.


• Use a
  pillow to raise your feet while you sleep, or raising the foot of the bed,
  these may help prevent attacks.

Should your symptoms persist or
worsen, then you should be examined by a physician.